Publication Date

Development of Single Molecule Techniques for Sensing and Manipulation of CRISPR and Polymerase Enzymes

May 2023

Chu, J., Romero, A., Taulbee, J. and Aran, K. (2023), Development of Single Molecule Techniques for Sensing and Manipulation of CRISPR and Polymerase Enzymes. Small 2300328. https://doi.org/10.1002/smll.202300328

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A Single Multiomics Transistor for Electronic Detection of SARS-Cov2 Variants Antigen and Viral RNA Without Amplification

April 2023

Ban, D.K., Hajian, R., Winton, A.J., Eom, R., Gupta, A., Kane, A.A., Liu, S., Sampath, R., Farrell, M.L., Coppock, M.B., Goldsmith, B. and Aran, K. (2023), A Single Multiomics Transistor for Electronic Detection of SARS-Cov2 Variants Antigen and Viral RNA Without Amplification. Adv. Mater. Technol. 2201945. https://doi.org/10.1002/admt.202201945.

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Emerging Biosensing Technologies for the Diagnostics of Viral Infectious Diseases

March 2022

Gözde Kabay, Jonalyn DeCastro, Alara Altay, Katherine Smith, Hsiang-Wei Lu, Antonia McDonnell Capossela, Maryam Moarefian, Kiana Aran, and Can Dincer. "Emerging Biosensing Technologies for the Diagnostics of Viral Infectious Diseases." Advanced Materials (Wiley) 2022, 2201085. https://doi.org/10.1002/adma.202201085.

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The Promise of Graphene-Based Transistors for Democratizing Multiomics Studies

September 2021

H.-W. Lu, A. Kane, J. Parkinson, Y. Gao, R. Hajian, M. Heltzen, B. Goldsmith, and K. Aran. “The Promise of Graphene-Based Transistors for Democratizing Multiomics Studies.” Biosensors and Bioelectronics, September 8, 2021, 113605. https://doi.org/10.1016/j.bios.2021.113605.

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Erythrocytes, a New Contributor to Age-Associated Loss of Blood–Brain Barrier Integrity

August 2021

Amiri, P., DeCastro, J., Littig, J., Lu, H.-W., Liu, C., Conboy, I., Aran, K., Erythrocytes, a New Contributor to Age-Associated Loss of Blood–Brain Barrier Integrity. Adv. Sci. 2021, 2101912. https://doi.org/10.1002/advs.202101912

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Diversification of the CRISPR Toolbox: Applications of CRISPR-Cas Systems Beyond Genome Editing

June 2021

S. Balderston, G. Clouse, J. Ripoll, G. Pratt, G. Gasiunas, J. Bock, E.P. Bennett, and K. Aran. Diversification of the CRISPR Toolbox: Applications of CRISPR-Cas Systems Beyond Genome Editing. The CRISPR Journal. Jun 2021.400-415.http://doi.org/10.1089/crispr.2020.0137

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Rapid and Electronic Identification and Quantification of Age‐Specific Circulating Exosomes via Biologically Activated Graphene Transistors

April 2021

Hajian, R., DeCastro, J., Parkinson, J., Kane, A., Camelo, A. F. R., Chou, P. P., Yang, J., Wong, N., Hernandez, E. D. O., Goldsmith, B., Conboy, I., Aran, K., Rapid and Electronic Identification and Quantification of Age‐Specific Circulating Exosomes via Biologically Activated Graphene Transistors. Adv. Biology 2021, 2000594. https://doi.org/10.1002/adbi.202000594

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Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor

April 2021

S. Balderston, J. Taulbee, E. Celaya, K. Fung, K. Smith, R. Hajian, G. Gasiunas, S. Kutanovas, R. Peytavi, F. Barron, B.R. Goldsmith, P. G. Collins, I. M. Conboy, V. Siksnys, K. Aran, Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor. Nature Biomedical Engineering, 2021, DOI 10.1038/s41551-021-00706-z

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The Microfluidic Toolbox for Analyzing Exosome Biomarkers of Aging

January 2021

J. DeCastro, J. Littig, P.P. Chou, J. Mack-Onyeike, A. Srinivasan, M.J. Conboy, I. M. Conboy, & K. Aran. The Microfluidic Toolbox for Analyzing Exosome Biomarkers of Aging. Molecules (Basel, Switzerland), 26(3), 535 (2021).

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Properties and Applications of Functionalized Graphene Oxide

October 2019

R. Hajian, K. Fung, P. Chou, S. Wang, S. Balderston, K. Aran, Graphene Oxide: Properties and Functionalization Methods. Material Matters, 2019, Vol. 14, Issue 1, 37-45

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Structural determination of Enzyme-Graphene Nanocomposite Sensor Material

October 2019

D. K. Rai, M. Gurusaran, V. Urban, K. Aran, L. Ma, P. Li, S. Qian, T.N. Narayanan, P.M. Ajayan, D. Liepmann, K. Sekar, M.E. Álvarez-Cao, J.J. Escuder-Rodríguez, M.E Cerdán, M.I. González-Siso, S. Viswanathan, R. Paulmurugan, V. Renugopalakrishnan. Sci Rep 9, 15519 (2019) DOI:10.1038/s41598-019-51882-7

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Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor.

March 2019

Reza Hajian, Sarah Balderston, Thanhtra Tran, Tara deBoer, Jessy Etienne, Mandeep Sandhu, Noreen A. Wauford, Jing-Yi Chung, Jolie Nokes, Mitre Athaiya, Jacobo Paredes, Regis Peytavi, Brett Goldsmith, Niren Murthy, Irina M. Conboy, Kiana Aran. (2019). Nature Biomedical Engineering doi: 10.1038/s41551-019-0371

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Graphene-based biosensor for on-chip detection of Bio-orthogonally Labeled Proteins to Identify the Circulating Biomarkers of Aging during Heterochronic Parabiosis.

September 2018

Sadlowski, C. M., Balderston, S., Sandhu, M., Hajian, R., Liu, C., Tran, T. T., ... & Aran, K. (2018). Lab on a Chip. https://doi.org/10.1039/C8LC00446C

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An Oral Microjet Vaccination System Elicits Antibody Production In Rabbits.

March 2017

Aran, K., Chooljian, M., Paredes, J., Rafi, M., Lee, K., Kim, A. Y., An, J., Yau, J. F., Chum, H., Conboy I., Murthy, N., Liepmann, D. (2017). An oral microjet vaccination system elicits antibody production in rabbits. Science Translational Medicine, 9(380). ttp://stm.sciencemag.org/content/9/380/eaaf6413.abstract

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In Vivo Delivery Of Transcription Factors With Multifunctional Oligonucleotides

November 2015

Lee, K., Mohammad, R., Wang, X., Aran, K., Feng, X., Sterzo L., C., … Murthy, N. (n.d.). In vivo delivery of transcription factors with multifunctional oligonucleotides. Natural Materials, 14(7), 701–706. https://doi.org/10.1016/j.bbamem.2015.02.010.Cationic

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Graphene-protein Field Effect Biosensors: Glucose Sensing

November 2015

Viswanathan, S., Narayanan, T. N., Aran, K., Fink, K. D., Paredes, J., Ajayan, P. M., … Renugopalakrishanan, V. (2015). Graphene-protein field effect biosensors: Glucose sensing. Materials Today, 18(9), 513–522. https://doi.org/10.1016/j.mattod.2015.04.003

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Stimuli-responsive Electrodes Detect Oxidative Stress And Liver Injury

December 2014

Aran, K., Parades, J., Rafi, M., Yau, J. F., Acharya, A. P., Zibinsky, M., Liepmann, D. and Murthy, N. (2015), Stimuli-Responsive Electrodes Detect Oxidative Stress and Liver Injury. Adv. Mater., 27: 1433–1436. doi:10.1002/adma.201404562
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A Turn-off Fluorescent Substrate For Horseradish Peroxidase Improves The Sensitivity Of Elisas

September 2014

Acharya, A.P., Sen, P., Aran, K., Gardner, A.B., Rafi, M., Dean, D., Murthy, N. Journal of Polymer Science Part A: Polymer Chemistry 53 (2), 206-210 doi:10.1002/pola.27376

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Graphene Protein Field Effect Biomedical Sensor for Glucose Measurements

March 2014

D. Liepmann, K. Aran, PM. Ajayan, S. Viswanathan, P. Li, V. Renugopalakrishnan, MRS Proceedings, 2014, DOI: 10.1557/opl.2015.302

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An Enzyme-free Digital Biosensor for Detection of Reactive Oxygen species

January 2014

K. Aran, J. Paredes, J. Yau. M. Rafi. MicroTAS 2014, Miniaturized Systems for Chemistry and Life Sciences.

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Continuous Monitoring Of Inflammation Biomarkers During Simulated Cardiopulmonary Bypass Using A Microfluidic Immunoassay Device—a Pilot Study

January 2013

Sasso, L.A., Aran, K., Guan, Y., Ündar, AZahn, J.D. Artificial organs 37 (1) doi.org/10.1111/aor.12021

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Microfiltration Platform For Continuous Blood Plasma Protein Extraction From Whole Blood During Cardiac Surgery

September 2011

Aran, K., Fok, A., Sasso, L. A., Kamdar, N., Guan, Y., Sun, Q., … Zahn, J. D. (2011). Microfiltration platform for continuous blood plasma protein extraction from whole blood during cardiac surgery. Lab on a Chip, 11(17), 2858–2868. http://doi.org/10.1039/c1lc20080a

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Translational Research In Pediatric Extracorporeal Life Support Systems And Cardiopulmonary Bypass Procedures: 2011 Update

July 2011

Qiu, F., Talor, J., Zahn, J., Pauliks, L., Kunselman, A. R., Palanzo, D., … Ündar, A. (2011). Translational Research in Pediatric Extracorporeal Life Support Systems and Cardiopulmonary Bypass Procedures: 2011 Update. World Journal for Pediatric and Congenital Heart Surgery, 2(3), 476–481. doi.org/10.1177%2F2150135111402226

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Differential Immune Activation During Simulated Cardiopulmonary Bypass Procedure Using Freshly Drawn And Week-old Blood—a Pilot Study

November 2010

Aran, K., Fok, A., Y, G., Sun, Q., Zahn, J., & Undar, A. (n.d.). Differential immune activation during simulated cardiopulmonary bypass procedure using freshly drawn and week-old blood—a pilot study. Artificial Organs, 34(11), 1048–53. https://www.ncbi.nlm.nih.gov/pubmed/21137157

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Irreversible, Direct Bonding Of Nanoporous Polymer Membranes To Pdms Or Glass Microdevices

January 2010

Aran, K., Sasso, L. A., Kamdar, N., & Zahn, J. D. (2010). Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices. Lab on a Chip, 10(5), 548. https://doi.org/10.1039/b924816a

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